Next-Generation Scientific Discovery, Modeling & Analytics
Led by Dr. Kevin Muñoz Forti, MSc, PhD, the Drift Lab pioneers computational biology frameworks, high-dimensional single-cell metabolomics, and rigorous mathematical methodologies engineered for reproducible biomedical discovery.
Core Research Directions
Bridging computational algorithm design, multi-omics data integration, and clinical translation.
Metabolic Reprogramming in Oncology
Investigating non-canonical nutrient dependencies, mitochondrial kinetics, and metabolic vulnerabilities across solid tumor microenvironments.
Single-Cell & Spatial Transcriptomics
Developing robust algorithmic frameworks to unmix complex cellular states, characterize immune-stromal cross-talk, and resolve cell-cell signaling dynamics.
Mathematical Kinetics & Nonlinear Modeling
Engineering analytical pipelines for dose-response pharmacodynamics, enzyme kinetics, and multi-variable parameter optimization.
Reproducible Computational Science
Developing high-integrity biostatistical workflows with cryptographic session provenance to guarantee audit-ready scientific reproducibility.
Resources
Scientific computing platforms, biostatistical tools, and analytical suites developed by the Drift Lab.
Plot Twist
Next-Generation Scientific Biostatistics, Nonlinear Curve-Fitting & Publication Graphics
Plot Twist is an open-source, publication-grade biostatistics, nonlinear curve-fitting, and data visualization suite engineered as a transparent alternative to proprietary legacy software. Built from the ground up for reproducible scientific discovery, Plot Twist combines clean spreadsheet data management, mathematical rigor, cryptographic data provenance, and 1200 DPI vector graphic exports.
8 Scientific Table Types
Dedicated spreadsheet models for Column replicates, XY titration series, Two-Way Grouped factorials, Contingency counts, Survival (Kaplan-Meier), Parts of Whole, High-Dimensional variables, and Nested biological hierarchies.
Dose-Response & Curve Fitting
Automated 4-Parameter Logistic (4PL) regression with $IC_50$ / $EC_50$, Top, Bottom, and Hill Slope estimation. Parametric and nonparametric ANOVA with Tukey HSD, Dunnett, Welch's tests, and Michaelis-Menten kinetics.
Single-Cell Omics & scRNA
Integrated dimensionality reduction (UMAP, t-SNE), marker gene violin distributions, and high-dimensional spectral expression heatmaps for single-cell and flow cytometry data.
1200 DPI Super-Chart Engine
24 scientific publication presets and 41 specialized palettes (Nature, Science, Viridis, Plasma). Real-time vector rendering with direct export to SVG, publication PDF, and high-res TIFF.
Cryptographic SHA-256 Provenance
Every calculation, mathematical transform, and figure parameter is cryptographically hashed with SHA-256 session integrity for tamper-proof reproducibility and audit-ready publications.
Multi-User Lab Server Architecture
Enterprise multi-member support with 50 GB isolated user home drives, PI Master PIN authorization, live storage meters, and secure browser streaming via containerized WebTop infrastructure.
Internal Validation & Peer Review
Plot Twist is currently deployed internally on our private lab computing clusters for rigorous numerical validation, cross-platform benchmarking, and peer-review verification. Standalone distributions (Windows, macOS, and Linux) will be made publicly available upon completion of laboratory validation.